CHOLECALCIFEROL IMPROVES GLYCEMIC CONTROL IN TYPE 2 DIABETIC PATIENTS: A 6-MONTH PROSPECTIVE INTERVENTIONAL STUDY

Cholecalciferol improves glycemic control in type 2 diabetic patients: a 6-month prospective interventional study

Aml Mohamed Nada,1 Dalia Shaheen2 1Faculty of Medicine, Department of Internal Medicine, 2Faculty of Medicine, Department of Medical Biochemistry, Mansoura University, Mansoura, Egypt Background and purpose: To investigate the effects of vitamin D supplementation on glucose homeostasis and lipid profile in type 2 diabetic patients who have vitamin

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Proveniences in Copies of Grammar of Meletius Smotrytsky (Evie, 1619) from the Collection of the Russian State Library

Slavic SANTASAPINA BONBONS Grammar of Meletius Smotritsky (Evie, 1619) is the most important scientific and educational work.This book has had a significant role in the development of education, science and culture in the XVII-XVIII centuries.The surviving copies of the first edition of the work of Meletius Smotritsky are of great scientific intere

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Safer Systems: People Training or System Tuning?

Safety is usually seen as a problem when it is absent rather than when it is present, where accidents, incidents, and the like represent a lack of safety rather than the presence of safety.To explain this lack of safety, one or more causes must be found.In the management of industrial safety, the human factor has traditionally been seen as a weak e

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Performance of crisis standards of care guidelines in a cohort of critically ill COVID-19 patients in the United States

Summary: Many US states published Connectors crisis standards of care (CSC) guidelines for allocating scarce critical care resources during the COVID-19 pandemic.However, the performance of these guidelines in maximizing their population benefit has not been well tested.In 2,272 adults with COVID-19 requiring mechanical ventilation drawn from the S

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Study of interaction energies between residues of the active site of Hsp90 and geldanamycin analogues using quantum mechanics/molecular mechanics methods [version 1; peer review: 2 approved]

Background: Heat shock protein (Hsp90KDa) is a Flash Dust molecular chaperone involved in the process of cellular oncogenesis, hence its importance as a therapeutic target in clinical trials.Geldanamycin is an inhibitor of Hsp90 chaperone activity, which binds to the ATP binding site in the N-terminal domain of Hsp90.However, geldanamycin has shown

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